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Home >> Antibodies >> PTP4A2 Antibody

PTP4A2 Antibody (F54431)

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  Catalog No Formulation Size Price (USD)  
Image F54431-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54431-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of human NCI-H460 cell lysate with PTP4A2 antibody. Predicted molecular weight ~19 kDa.
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Western blot testing of human NCI-H460 cell lysate with PTP4A2 antibody. Predicted molecular weight ~19 kDa.
Western blot testing of human HeLa cell lysate with PTP4A2 antibody. Predicted molecular weight ~19 kDa.
Immunofluorescent staining of human prostate carcinoma cells with PTP4A2 antibody (green) PI (red).
IHC testing of FFPE human prostate carcinoma tissue with PTP4A2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Flow cytometry testing of human WiDr cells with PTP4A2 antibody; Blue=isotype control, Green= PTP4A2 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt Q12974
Applications Immunofluorescence : 1:25
Flow cytometry : 1:25 (1x10e6 cells)
Immunohistochemistry (FFPE) : 1:25
Western blot : 1:500-1:2000
Limitations This PTP4A2 antibody is available for research use only.
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  • Applications : WB, IHC-P, FACS
    Reactivity : Human, Mouse, Rat

Description

PTP4A2 belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity.

Application Notes

The stated application concentrations are suggested starting points. Titration of the PTP4A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 32-59 from the human protein was used as the immunogen for the PTP4A2 antibody.

Storage

Aliquot the PTP4A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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