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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Protein phosphatase 1 regulatory subunit 15A also known as growth arrest and DNA damage-inducible protein GADD34 is a protein that in humans is encoded by the PPP1R15A gene. Enables protein phosphatase binding activity and protein phosphatase regulator activity. Involved in several processes, including peptidyl-serine dephosphorylation; regulation of gene expression; and regulation of protein modification process. Acts upstream of or within endoplasmic reticulum unfolded protein response. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and mitochondrion. Predicted to be part of protein phosphatase type 1 complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and liver. Used to study thalassemia. Orthologous to human PPP1R15A (protein phosphatase 1 regulatory subunit 15A).
Visit our GADD34 Antibody / Stress Response Protein Antibody page to explore additional validated antibodies and research tools for investigating GADD34 biology, integrated stress response signaling, and translational regulation.
Optimal dilution of the Ppp1r15a antibody should be determined by the researcher.
Recombinant mouse protein (amino acids R14-R572) was used as the immunogen for the Ppp1r15a antibody.
After reconstitution, the Ppp1r15a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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