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Home >> Antibodies >> Phospho-Dnmt1 Antibody (pS1105)

Phospho-Dnmt1 Antibody (pS1105) (F48686)

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  Catalog No Formulation Size Price (USD)  
Image F48686-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48686-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Dot blot analysis of phospho-Dnmt1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Dot blot analysis of phospho-Dnmt1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P26358
Applications Dot blot : 1:500
Limitations This phospho-Dnmt1 antibody is available for research use only.
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Description

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [Wiki]

Application Notes

Titration of the phospho-Dnmt1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This phospho-Dnmt1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS1105 of human Dnmt1.

Storage

Aliquot the phospho-Dnmt1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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