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Home >> Antibodies >> PARK8 Antibody

PARK8 Antibody [clone 133AT1218] (F40408)

  Catalog No Formulation Size Price (USD)  
Image F40408-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40408-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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The PARK8 antibody used in western blot to detect LRRK2/PARK8 in mouse brain cell lysate
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 133AT1218
Purity Purified
UniProt Q5S007
Applications Western blot : 1:100-1:500
Limitations This PARK8 antibody is available for research use only.
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Description

This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

Application Notes

Titration of the PARK8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This PARK8 antibody was raised in mice using purified His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.

Storage

Aliquot the PARK8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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