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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space.
Titration of the OPA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This OPA1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 895-929 amino acids from the C-terminal region of human OPA1, form S1.
Aliquot the OPA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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