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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Notch1 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. It is involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. [UniProt]
Titration of the Notch1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This Notch1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2403-2437 amino acids from the C-terminal region of mouse Notch1.
Aliquot the Notch1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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