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Home >> Antibodies >> MTAP Antibody / MTA phosphorylase

MTAP Antibody / MTA phosphorylase [clone 28M98] (RQ8644)

  Catalog No Formulation Size Price (USD)  
Image RQ8644 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 439
Microvalidated Recrabbitmono
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Western blot testing of 1) human 293T and 2) mouse NIH 3T3 cell lysate with MTAP antibody. Expected molecular weight: 26-38 kDa (multiple isoforms).
Immunoprecipitation of MTAP protein from human HeLa whole cell lysate using MTAP antibody at 1:50.
Availability 1-3 days
Species Reactivity Human, Mouse
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name 28M98
Purity Affinity chromatography
UniProt Q13126
Applications Western Blot : 1:500-1:2000
Immunoprecipitation : 1:50
Limitations This MTAP antibody is available for research use only.
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Description

Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. [UniProt]

Application Notes

Optimal dilution of the MTAP antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human MTAP protein was used as the immunogen for the MTAP Antibody.

Storage

Store the MTAP antibody at -20oC.

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