MSH6 Antibody / DNA Mismatch Repair Protein Antibody [clone MSH6/3085] (V7417)

MSH6 Antibody in Human Colon Carcinoma IHC. Immunohistochemistry testing of MSH6 Antibody / DNA Mismatch Repair Protein Antibody in FFPE human colon carcinoma tissue. Heat-induced epitope retrieval was performed by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling prior to staining. This MSH6 Antibody demonstrates nuclear detection of the DNA mismatch repair protein in human colon tumor tissue

MSH6 Antibody in Human Colon Carcinoma IHC. Immunohistochemistry testing of MSH6 Antibody / DNA Mismatch Repair Protein Antibody in FFPE human colon carcinoma tissue. Heat-induced epitope retrieval was performed by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling prior to staining. This MSH6 Antibody demonstrates nuclear staining consistent with the established localization of MSH6.

MSH6 Antibody in Human HeLa Cervical Cancer Cells WB. Western blot testing of MSH6 Antibody / DNA Mismatch Repair Protein Antibody in human HeLa cervical cancer cell lysate. A prominent high-molecular-weight band is detected within the expected range of approximately 120-160 kDa for MSH6. This MSH6 Antibody demonstrates detection of the DNA mismatch repair protein in human HeLa cells.

MSH6 Antibody in Human HCT-116 Colorectal Cancer Cells WB. Western blot testing of MSH6 Antibody / DNA Mismatch Repair Protein Antibody in human HCT-116 colorectal cancer cell lysate. A prominent band is detected near the predicted molecular weight of approximately 160 kDa for MSH6. This MSH6 Antibody demonstrates detection of the mismatch repair protein in human colorectal cancer cells.

MSH6 Antibody in Human MCF7 Breast Cancer Cells IF. Immunofluorescence testing of MSH6 Antibody / DNA Mismatch Repair Protein Antibody in permeabilized human MCF7 breast cancer cells. MSH6 antibody staining is shown in green and phalloidin staining of filamentous actin is shown in red. This MSH6 Antibody demonstrates nuclear detection consistent with the established subcellular localization of MSH6.

MSH6 Antibody Protein Microarray Validation. Protein microarray analysis of MSH6 Antibody / DNA Mismatch Repair Protein Antibody using a HuProt microarray containing more than 19,000 full-length human proteins. Z-scores represent antibody-binding signal strength in standard deviations above the mean signal across the array, while the S-score represents the difference between the highest and next-highest Z-scores and provides a measure of relative target specificity. This analysis evaluates the binding specificity of clone MSH6/3085 across the human proteome.

MSH6 Antibody Purity Analysis by SDS-PAGE. Electrophoretic analysis of purified, BSA-free MSH6 Antibody / DNA Mismatch Repair Protein Antibody to evaluate antibody purity and integrity. The observed antibody protein pattern supports the integrity and purity of the MSH6/3085 monoclonal antibody preparation.