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Home >> Antibodies >> Mesothelin Antibody

Mesothelin Antibody (R32262)

  Catalog No Formulation Size Price (USD)  
Image R32262 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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IHC testing of FFPE mouse lung with Mesothelin antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q61468
Localization Cytoplasmic, cell surface, secreted
Applications Immunohistochemistry (FFPE) : 0.5-1ug/ml
Limitations This Mesothelin antibody is available for research use only.
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Description

Mesothelin, also known as MSLN or MPF, is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

Application Notes

Optimal dilution of the Mesothelin antibody should be determined by the researcher.

Immunogen

Amino acids 308-576 of mouse Mesothelin were used as the immunogen for the Mesothelin antibody.

Storage

After reconstitution, the Mesothelin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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