Mesothelin Antibody / Mesothelioma Marker Antibody [clone MSLN/3384] (V8529)

Mesothelin Antibody Mesothelioma IHC. Immunohistochemistry analysis of mesothelin expression in FFPE human lung mesothelioma using clone MSLN/3384. Distinct membranous HRP-DAB brown staining highlights tumor cell surfaces with focal cytoplasmic signal, consistent with cell surface localization of MSLN. The staining pattern clearly delineates mesothelioma cells from surrounding stromal components, supporting its use as a mesothelioma marker in tissue sections. Heat-induced epitope retrieval was performed in pH 9 Tris-EDTA buffer.

Mesothelioma Marker Antibody in Lung Tumor Tissue. Mesothelin antibody staining of FFPE human lung mesothelioma demonstrates strong membranous labeling of tumor cells using clone MSLN/3384. The crisp cell surface staining pattern emphasizes mesothelial differentiation and provides clear contrast against non-neoplastic tissue. This expression profile is consistent with known mesothelin distribution in mesothelioma. HIER: boiling in pH 9 Tris with EDTA followed by cooling prior to staining.

Mesothelin / MSLN Antibody Lung Mesothelioma IHC. Immunohistochemical detection of mesothelin (MSLN) in FFPE human lung mesothelioma using clone MSLN/3384 reveals prominent membranous HRP-DAB staining with partial cytoplasmic localization. Tumor cells exhibit strong, continuous surface labeling, aiding visualization of tumor architecture and mesothelial origin. The observed staining pattern aligns with established mesothelin expression in mesothelioma. Heat-induced epitope retrieval was performed using pH 9 Tris-EDTA buffer.

Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Mesothelin antibody (clone MSLN/3384). These results demonstrate the foremost specificity of the MSLN/3384 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.

SDS-PAGE analysis of purified, BSA-free Mesothelin antibody (clone MSLN/3384) as confirmation of integrity and purity.