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Home >> Antibodies >> Mesothelin Antibody / MSLN

Mesothelin Antibody / MSLN [clone MSLN/2132] (V5641)

  Catalog No Formulation Size Price (USD)  
Image V5641-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5641-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5641SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
Bulk quote request
Western blot testing of human OVCAR-3 cell lysate with Mesothelin antibody (clone MSLN/2132). Predicted molecular weight ~69 kDa (precursor), ~40 kDa (cleaved form). Glycosylation may make the protein run higher than expected.
SDS-PAGE analysis of purified, BSA-free Mesothelin antibody (clone MSLN/2132) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name MSLN/2132
Purity Protein G affinity
UniProt Q13421
Localization Cell membrane, Golgi apparatus, Secreted
Applications Western Blot : 1-2ug/ml
Limitations This Mesothelin antibody is available for research use only.
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Description

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Application Notes

Optimal dilution of the Mesothelin antibody should be determined by the researcher.

Immunogen

A portion of amino acids 273-407 from human Mesothelin protein was used as the immunogen for the Mesothelin antibody.

Storage

Aliquot the Mesothelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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