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Home >> Antibodies >> LRIG2 Antibody / Leucine-rich repeats and immunoglobulin-like domains protein 2

LRIG2 Antibody / Leucine-rich repeats and immunoglobulin-like domains protein 2 (RQ8477)

  Catalog No Formulation Size Price (USD)  
Image RQ8477 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 439
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Immunofluorescent staining of FFPE human HeLa cells with LRIG2 antibody (red).
Western blot testing of human 1) K562 and 2) HEL cell lysate with LRIG2 antibody. Predicted molecular weight ~119 kDa.
Flow cytometry testing of fixed and permeabilized human K562 cells with LRIG2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= LRIG2 antibody.
Availability 1-3 days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt O94898
Localization Cytoplasm, Nucleus
Applications Western Blot : 0.5-1ug/ml
Immunofluorescence : 5ug/ml
Flow Cytometry : 1-3ug/million cells
ELISA : 0.1-0.5ug/ml
Limitations This LRIG2 antibody is available for research use only.
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Description

This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the LRIG2 antibody should be determined by the researcher.

Immunogen

An E.coli-derived human recombinant protein (amino acids E108-R977) was used as the immunogen for the LRIG2 antibody.

Storage

After reconstitution, the LRIG2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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