- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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KLF4 Antibody recognizes Kruppel-like factor 4, a member of the Kruppel-like family of zinc finger transcription factors that regulates gene expression involved in cell fate decisions. KLF4 functions primarily within the nucleus, where it controls transcriptional programs governing proliferation, differentiation, cell cycle arrest, and survival. Through these activities, it contributes to the maintenance of normal tissue architecture and cellular identity.
KLF4 is especially abundant in epithelial tissues and is well known for its role in preserving epithelial homeostasis and regulating differentiation. It also participates in stem cell maintenance, tissue regeneration, and cellular responses to environmental stress. Depending on biological context, altered KLF4 expression has been associated with developmental disorders, inflammatory diseases, and numerous types of cancer.
Because of its broad regulatory functions, KLF4 Antibody is widely used to evaluate protein expression and nuclear localization in cultured cells and tissue sections. A KLF4 Antibody is a valuable research tool for investigations of transcriptional regulation, epithelial biology, stem cell research, cancer progression, and developmental processes.
Learn more about KLF4 biology and its role as a stem cell-associated transcription factor by visiting our KLF4 Antibody / Stem Cell Transcription Factor Antibody page.
Optimal dilution of the KLF4 antibody should be determined by the researcher.
A synthetic peptide specific to human KLF4 was used as the immunogen for the KLF4 antibody.
Store the KLF4 antibody at -20oC.
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