Kallikrein 5 Antibody / Epidermal Barrier Protease Antibody [clone KLK5/3841] (V8212)

Kallikrein 5 Antibody Skin IHC. Immunohistochemistry analysis of FFPE human skin tissue stained with Kallikrein 5 Antibody demonstrates strong linear and cytoplasmic HRP-DAB brown staining within the superficial epidermal keratinocyte layers, consistent with KLK5-associated serine protease expression involved in epidermal barrier regulation and desquamation pathways. This epidermal barrier protease antibody highlights epithelial differentiation-associated signaling and cutaneous barrier homeostasis within stratified squamous epithelium. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.

Kallikrein 5 Antibody Human Skin Tissue IHC. Immunohistochemistry analysis of FFPE human skin tissue stained with Kallikrein 5 Antibody demonstrates strong epithelial-associated HRP-DAB brown staining surrounding follicular and superficial epidermal structures, consistent with KLK5-associated serine protease expression involved in epithelial differentiation and epidermal barrier regulation. This epidermal barrier protease antibody highlights keratinocyte-associated proteolytic signaling pathways within cutaneous tissue compartments. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.

Kallikrein 5 Antibody Protein Microarray Validation. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Kallikrein 5 Antibody demonstrates highly selective recognition of KLK5 with exceptionally strong separation from non-target proteins across the tested human proteome. These results demonstrate the foremost specificity of the KLK5/3841 mAb and support highly specific detection of epithelial protease-associated signaling pathways and epidermal barrier regulatory proteins. The Z-score represents the strength of antibody binding signal relative to the overall array mean, while the S-score reflects target specificity relative to the next highest ranked protein signal. The markedly elevated S-score separation observed for KLK5 supports preferential target recognition with minimal off-target binding across the tested human proteome.

SDS-PAGE analysis of purified, BSA-free Kallikrein 5 antibody (clone KLK5/3841) as confirmation of integrity and purity.