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Home >> Antibodies >> ITGA5 Antibody / Integrin alpha 5

ITGA5 Antibody / Integrin alpha 5 [clone IDB-9] (RQ5245)

  Catalog No Formulation Size Price (USD)  
Image RQ5245 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 439
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Western blot testing of mouse heart lysate with ITGA5 antibody. Expected molecular weight: 115-160 kDa depending on glycosylation level. An ~25 kDa band corresponding to the ITGA5 light chain may also be detected.
Availability 1-2 weeks
Species Reactivity Human, Mouse
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name IDB-9
Purity Affinity purified
UniProt P08648
Applications Western Blot : 1:1000-1:2000
Limitations This ITGA5 antibody is available for research use only.
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Description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [RefSeq]

Application Notes

Optimal dilution of the ITGA5 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Integrin alpha 5 / ITGA5 was used as the immunogen for the ITGA5 antibody.

Storage

Store the ITGA5 antibody at -20oC.

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