IRF6 Antibody / Epithelial Development Transcription Factor Antibody (R36249)

IRF6 Antibody Human Ovary WB. Western blot analysis of IRF6 expression was performed using anti-IRF6 antibody in human ovary lysate. IRF6, also known as Interferon Regulatory Factor 6, is a DNA-binding transcription factor that regulates epithelial differentiation, tissue morphogenesis, and developmental signaling. A specific immunoreactive band is detected at approximately 53/42 kDa, corresponding to the predicted molecular weights of IRF6 isoforms 1 and 2. Expression in ovarian tissue is consistent with the role of IRF6 in regulating cellular differentiation and maintaining epithelial homeostasis. These results support the utility of IRF6 Antibody for studies of developmental biology, epithelial differentiation, and transcriptional regulation.

IRF6 Antibody HEK293 Overexpression WB. Western blot analysis of IRF6 expression was performed using anti-IRF6 antibody in HEK293 cells transiently overexpressing IRF6. Lane 1: mock-transfected HEK293 lysate. Lane 2: IRF6-overexpressing HEK293 lysate. IRF6, also known as Interferon Regulatory Factor 6, is a DNA-binding transcription factor that regulates epithelial differentiation, tissue morphogenesis, and developmental signaling. A prominent immunoreactive band is detected at approximately 53 kDa in the IRF6-transfected sample, corresponding to the predicted molecular weight of IRF6 isoform 1 (~53 kDa). Minimal signal is observed in the mock-transfected control, supporting the specificity of IRF6 detection. These results support the utility of IRF6 Antibody for studies of developmental biology, epithelial differentiation, and transcriptional regulation.

IRF6 Antibody Human Kidney IHC. IHC staining of FFPE human kidney with IRF6 antibody demonstrated strong nuclear staining of renal tubular epithelial cells, consistent with the localization of IRF6 (Interferon Regulatory Factor 6), a DNA-binding transcription factor involved in epithelial differentiation and tissue homeostasis. IRF6 regulates gene expression programs that control cellular maturation, morphogenesis, and maintenance of epithelial integrity. The prominent nuclear staining observed in renal tubules is consistent with the role of IRF6 as a transcriptional regulator in differentiated epithelial tissues. Immunostaining was performed with IRF6 antibody at 2.5 ug/ml using an alkaline phosphatase detection system. Heat-induced epitope retrieval was achieved by steaming tissue sections in pH 6 citrate buffer prior to staining.

IRF6 Antibody Human Prostate IHC. IHC staining of FFPE human prostate tissue with IRF6 antibody demonstrated strong nuclear staining of glandular epithelial cells, consistent with the localization of IRF6 (Interferon Regulatory Factor 6), a DNA-binding transcription factor involved in epithelial differentiation and tissue morphogenesis. IRF6 regulates gene expression programs that maintain epithelial integrity and cellular homeostasis. The prominent nuclear staining observed in prostatic epithelium is consistent with the established role of IRF6 in differentiated epithelial tissues and transcriptional control. Immunostaining was performed with IRF6 antibody at 2.5 ug/ml using an alkaline phosphatase detection system. Heat-induced epitope retrieval was achieved by steaming tissue sections in pH 6 citrate buffer prior to staining.