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Home >> Antibodies >> IRF6 Antibody / Interferon Regulatory Factor 6

IRF6 Antibody / Interferon Regulatory Factor 6 [clone GHD-9] (RQ4714)

  Catalog No Formulation Size Price (USD)  
Image RQ4714 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 449
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IRF6 / Interferon Regulatory Factor 6 Antibody Human Jurkat WB. Western blot analysis of IRF6 expression was performed using anti-IRF6 antibody in human Jurkat cell lysate. IRF6, also known as Interferon Regulatory Factor 6, is a DNA-binding transcription factor that regulates epithelial differentiation, tissue morphogenesis, and developmental signaling. A prominent immunoreactive band is detected at approximately 53 kDa, corresponding to the predicted molecular weight of IRF6. Expression in Jurkat cells demonstrates the utility of this model for studying IRF6-mediated transcriptional regulation and signaling pathways. These results support the utility of IRF6 Antibody for studies of developmental biology, epithelial differentiation, and gene expression.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Host Rabbit
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name GHD-9
Purity Affinity purified
UniProt O14896
Applications Western Blot : 1:1000-1:2000
Limitations This IRF6 / Interferon Regulatory Factor 6 antibody is available for research use only.
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Description

IRF6 Antibody specifically detects Interferon Regulatory Factor 6, a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6.

Explore our IRF6 Antibody / Epithelial Development Transcription Factor Antibody page for additional information on this key regulator of epithelial differentiation, tissue morphogenesis, and developmental gene expression.

Application Notes

Optimal dilution of the IRF6 / Interferon Regulatory Factor 6antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human IRF6 was used as the immunogen for the IRF6 / Interferon Regulatory Factor 6 antibody.

Storage

Store the IRF6 / Interferon Regulatory Factor 6 antibody at -20oC.

Alternate Names

IRF6 antibody, Interferon Regulatory Factor 6 antibody, IRF-6 antibody, Developmental Transcription Factor antibody, Epithelial Differentiation Factor antibody, Cleft Lip and Palate Protein antibody

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