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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Interleukin 15 is a cytokine with the ability to stimulate the proliferation activity of Th1 and/or Th2 lymphocytes. This gene is mapped to human chromosome 4q31 by fluorescence in situ hybridization. IL15 is a novel cytokine whose effects on T-cell activation and proliferation are similar to those of interleukin-2 (IL-2), presumably because IL15 utilizes the beta and gamma chains of the IL-2 receptor. It can play a role in the initiation and outcome of acute and chronic rejection. Anti-IL-15 therapy in combination with classic immunosuppression therapy might be beneficial in the prevention of acute, and especially chronic, allograft rejection.
For an IL-15 monoclonal with complementary Western blot, IHC, and protein microarray validation, see our IL15 Antibody IL15/4354 / Interleukin-15 Monoclonal Antibody page.
The stated application concentrations are suggested starting amounts. Titration of the IL15 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 49-162) was used as the immunogen for this IL15 antibody.
After reconstitution, the IL15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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