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Home >> Antibodies >> IL-6 Antibody / Interleukin 6

IL-6 Antibody / Interleukin 6 [clone IL6/8713] (V5432)

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  Catalog No Formulation Size Price (USD)  
Image V5432-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5432-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5432SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
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IHC staining of FFPE human adrenal gland tissue with IL-6 antibody (clone IL6/8713). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human adrenal gland tissue with IL-6 antibody (clone IL6/8713). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgM, kappa
Clone Name IL6/8713
Purity Protein A/G affinity
UniProt P05231
Localization Cytoplasm, Extracellular (Secreted)
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This IL-6 antibody is available for research use only.
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Description

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. It plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6.It is involved in host defense, acute phase reactions, immune responses, and hematopoiesis.

Application Notes

Optimal dilution of the IL-6 antibody should be determined by the researcher.

Immunogen

A recombinant fragment (within amino acids 1-200) of human IL-6 protein was used as the immunogen for the IL-6 antibody.

Storage

Aliquot the IL-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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