- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1A as a susceptibility gene for pancreatic cancer.
Optimal dilution of the HNF1A antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
A portion of amino acids 214-339 from the human protein was used as the immunogen for the HNF1A antibody.
Store the HNF1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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