- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
HGFR Antibody (MET) [clone 4AT247] (F40183)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F40183-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F40183-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | 4AT247 |
| Purity | Purified |
| UniProt | P08581 |
| Applications | Western blot : 1:1000 Immunofluorescence : 1:100 |
| Limitations | This HGFR antibody (MET) is available for research use only. |
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The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
Titration of the HGFR antibody (MET) may be required due to differences in protocols and secondary/substrate sensitivity.
This HGFR antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.
Aliquot the HGFR antibody (MET) and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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