- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Titration of the HER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This HER2 antibody was produced from rabbits immunized with human recombinant ErbB2 protein.
Aliquot the HER2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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