- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Glycerol Kinase Antibody / Lipid Metabolism Enzyme Antibody recognizes glycerol kinase (GK), a cytosolic enzyme that catalyzes the ATP-dependent phosphorylation of glycerol to glycerol-3-phosphate. This reaction represents the first committed step in glycerol metabolism and links carbohydrate and lipid metabolic pathways by supplying intermediates for triglyceride synthesis, phospholipid production and energy generation. Because glycerol kinase occupies a central position in metabolic homeostasis, it is widely studied in the context of obesity, diabetes, liver function and inherited metabolic disorders. NSJ Bioreagents offers high-quality Glycerol Kinase Antibody reagents for investigating lipid metabolism and cellular energy regulation.
Glycerol-3-phosphate generated by glycerol kinase serves as an important precursor for the biosynthesis of triglycerides and membrane phospholipids while also contributing to glycolytic and gluconeogenic pathways. Glycerol kinase is expressed most abundantly in liver, kidney and other metabolically active tissues where it regulates glycerol utilization according to nutritional status and energy demand. Through its role in coordinating lipid storage and energy production, Glycerol Kinase Antibody is widely used to investigate metabolic adaptation, hepatic function and lipid homeostasis in both normal physiology and disease.
Mutations in the GK gene cause glycerol kinase deficiency, an inherited metabolic disorder characterized by impaired glycerol metabolism and variable clinical manifestations ranging from isolated hyperglycerolemia to complex multisystem disease. Altered glycerol kinase activity has also been investigated in obesity, insulin resistance, fatty liver disease and cancer metabolism, where metabolic reprogramming supports cellular growth and survival. Continued research has expanded understanding of how glycerol kinase contributes to lipid utilization, metabolic flexibility and whole-body energy balance across diverse physiological conditions.
A Glycerol Kinase Antibody is a valuable reagent for investigating glycerol metabolism, lipid homeostasis and cellular energy regulation. A Lipid Metabolism Enzyme Antibody supports research involving triglyceride biosynthesis, hepatic metabolism, metabolic disease, glycerol kinase deficiency and the molecular control of energy metabolism.
Researchers studying lipid metabolism, energy homeostasis and metabolic regulation may also be interested in our Metabolism Research Antibodies page, featuring antibodies against enzymes involved in carbohydrate, lipid and energy metabolism.
Optimal dilution of the Glycerol Kinase Antibody / Lipid Metabolism Enzyme Antibody should be determined by the researcher.
A recombinant human partial protein corresponding to amino acids M1-S180 was used as the immunogen for the Glycerol Kinase antibody.
After reconstitution, the Glycerol Kinase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Glycerol Kinase antibody, Lipid Metabolism Enzyme antibody, GK antibody, ATP:Glycerol 3-Phosphotransferase antibody
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