- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Glucagon Antibody / Pancreatic Hormone Antibody detects glucagon, a peptide hormone produced primarily by pancreatic alpha cells that plays a central role in glucose metabolism and endocrine regulation. Glucagon is encoded by the GCG gene and generated through tissue-specific processing of the proglucagon precursor. In pancreatic alpha cells, prohormone processing produces mature glucagon, which functions as a key counter-regulatory hormone to insulin and helps maintain glucose homeostasis through effects on metabolic tissues.
Glucagon is a major component of the endocrine pancreas and is widely studied in metabolic research, diabetes models and investigations of islet cell biology. Following secretion from pancreatic alpha cells, glucagon binds the glucagon receptor to activate signaling pathways involved in hepatic glucose production, glycogen metabolism and energy balance. Glucagon Antibody provides researchers with a tool to examine glucagon-producing cells, pancreatic islet organization and regulation of this important pancreatic hormone.
Research involving glucagon has expanded understanding of the complex interactions between pancreatic hormones that control nutrient availability and metabolic adaptation. Altered glucagon signaling has been investigated in studies of glucose imbalance, endocrine dysfunction and diabetes-related pathways. In addition to pancreatic expression, the GCG precursor gives rise to related peptides in intestinal and neuronal tissues, highlighting the importance of proglucagon processing in different biological systems.
Detection of glucagon expression is commonly used to identify pancreatic alpha cells and study endocrine cell development, differentiation and function. Analysis of glucagon-producing cells provides insight into islet architecture, hormone regulation and changes that occur during metabolic stress. Glucagon Antibody is valuable for researchers studying pancreatic biology, endocrine signaling and mechanisms controlling glucose homeostasis.
Glucagon Antibody applications include detection of glucagon expression and localization in biological samples using techniques such as immunohistochemistry, immunofluorescence, Western blot and related protein analysis methods. NSJ Bioreagents provides Glucagon Antibody / Pancreatic Hormone Antibody for researchers studying pancreatic hormones, alpha cell biology, glucose metabolism and endocrine regulation pathways.
Glucagon Antibody detects a pancreatic alpha cell hormone involved in glucose metabolism, endocrine signaling and energy balance, making it a useful marker for research areas featured in our Metabolism Antibodies page.
Optimal dilution of the Glucagon Antibody / Pancreatic Hormone Antibody should be determined by the researcher.
Amino acids HSQGTFTSDYSKYLDSRRAQDFVQWLMNT were used as the immunogen for the Glucagon antibody.
After reconstitution, the Glucagon antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
GCG Antibody, Proglucagon Antibody, Glucagon Peptide Antibody, Pancreatic Alpha Cell Marker Antibody, Enteroglucagon Antibody, Glucagon Hormone Antibody
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