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Home >> Antibodies >> GLP-1 Antibody / Incretin Hormone Antibody

GLP-1 Antibody / Incretin Hormone Antibody [clone AOHH-7] (RQ4965)

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Image RQ4965 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 449
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GLP-1 Antibody Human Fetal Pancreas WB. Western blot testing of human fetal pancreas lysate with GLP-1 Antibody. A specific band was detected at approximately 10 kDa. Although mature GLP-1 has a predicted molecular weight of approximately 3 kDa, higher molecular weight bands may be observed due to detection of proglucagon-derived processing intermediates and peptide forms generated during precursor cleavage. GLP-1 Antibody / Incretin Hormone Antibody, clone AOHH-7, supports studies of glucagon like peptide 1 expression, endocrine pancreas development, incretin signaling and glucose metabolism pathways.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Host Rabbit
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AOHH-7
Purity Affinity purified
UniProt P01275
Applications Western Blot : 1:1000-1:5000
Limitations This GLP-1 Antibody / Incretin Hormone Antibody is available for research use only.
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Description

GLP-1 Antibody / Incretin Hormone Antibody detects glucagon like peptide 1, a proglucagon-derived peptide hormone involved in glucose regulation, endocrine signaling and metabolic homeostasis. GLP-1 is generated through tissue-specific processing of the GCG precursor and is primarily produced by intestinal enteroendocrine L cells, with additional roles described in neuroendocrine research. This recombinant rabbit monoclonal antibody, clone AOHH-7, provides researchers with a tool for studying GLP-1 expression, localization and incretin hormone biology.

GLP-1 functions as an important incretin hormone that participates in communication between the gastrointestinal system and endocrine pancreas. Following nutrient stimulation, GLP-1 contributes to pathways regulating insulin secretion, glucagon modulation, appetite signaling and energy balance. Although glucagon and GLP-1 originate from the same proglucagon precursor, they are generated through different processing pathways and have distinct physiological activities. GLP-1 Antibody enables investigation of this specialized peptide hormone in metabolism and endocrine research applications.

Research involving GLP-1 has expanded significantly because of its central role in glucose metabolism, pancreatic islet regulation and metabolic disease pathways. Studies of GLP-1 expression provide insight into enteroendocrine cell biology, hormone secretion mechanisms and signaling networks that regulate nutrient responses. Recombinant rabbit monoclonal GLP-1 Antibody clone AOHH-7 supports analysis of this incretin pathway with a defined antibody format.

GLP-1 is also studied in relation to broader neuroendocrine and metabolic signaling systems, where peptide hormones coordinate communication between tissues. Detection of GLP-1-producing cells helps researchers examine endocrine differentiation, gastrointestinal hormone regulation and changes associated with metabolic research models.

GLP-1 Antibody applications include detection of glucagon like peptide 1 expression and localization in biological samples using techniques such as immunohistochemistry, immunofluorescence and related protein analysis methods. NSJ Bioreagents provides GLP-1 Antibody / Incretin Hormone Antibody, clone AOHH-7, for researchers studying incretin signaling, endocrine regulation, glucose metabolism and peptide hormone biology.

GLP-1 Antibody detects an incretin hormone generated from the proglucagon precursor and involved in metabolic regulation; additional GCG-derived peptide research tools are available on our Glucagon Antibody / Pancreatic Hormone Antibody page.

Application Notes

Optimal dilution of the GLP-1 Antibody / Incretin Hormone Antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Glucagon-like peptide 1 was used as the immunogen for the GLP-1 antibody.

Storage

Store the GLP-1 antibody at -20oC.

Alternate Names

Glucagon Like Peptide 1 Antibody, GLP1 Antibody, Incretin Hormone Antibody, GCG-Derived Peptide Antibody, Enteroendocrine Hormone Antibody, Insulin Secretion Regulator Antibody

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