FOLH1 Antibody / Prostate Cancer and PSMA Marker [clone FOLH1/2363] (V7505)

FOLH1 Antibody Prostate Cancer IHC. Immunohistochemistry analysis of FFPE human prostate carcinoma tissue stained with FOLH1 Antibody / Prostate Cancer and PSMA Marker. Tumor epithelial cells display strong membranous and cytoplasmic HRP-DAB brown staining consistent with expression of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA, a membrane-associated glycoprotein widely studied in prostate tumor biology and epithelial differentiation pathways. Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

FOLH1 Antibody Human Prostate Carcinoma IHC. Immunohistochemistry analysis of FFPE human prostate carcinoma tissue stained with FOLH1 Antibody / Prostate Cancer and PSMA Marker. Malignant glandular epithelial cells demonstrate strong membranous and apical cytoplasmic HRP-DAB brown staining consistent with expression of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA, a prostate-associated membrane glycoprotein involved in folate metabolism and prostate tumor-associated signaling pathways. Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

FOLH1 Antibody LNCaP WB. Western blot analysis of human LNCaP cell lysate using FOLH1 Antibody / Prostate Cancer and PSMA Marker. A strong band is detected at approximately 100 kDa, consistent with the predicted molecular weight of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA. The observed signal is consistent with established FOLH1 expression in prostate-derived tumor cell models and supports its role as a membrane-associated enzyme involved in prostate cancer-associated signaling and folate metabolism pathways.

FOLH1 Antibody Protein Microarray Validation. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using clone FOLH1/2363. These results demonstrate high specificity of the mouse monoclonal antibody for Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA, a membrane-associated metallopeptidase involved in prostate cancer biology, folate metabolism, and glutamatergic signaling pathways. Z- and S-score analysis confirms strong preferential binding to the intended target relative to non-specific proteins represented on the HuProt(TM) array. The Z-score represents the signal strength generated by antibody binding to an individual protein relative to the overall array background, while the S-score reflects the relative specificity gap between the top-ranked target and subsequent proteins on the array.

SDS-PAGE analysis of purified, BSA-free FOLH1 antibody as confirmation of integrity and purity.

FOLH1 Antibody Rat Kidney IHC. Immunohistochemistry analysis of FFPE rat kidney tissue stained with FOLH1 Antibody / Prostate Cancer and PSMA Marker. Renal tubular epithelial cells demonstrate apical membranous HRP-DAB brown staining consistent with expression of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA, a membrane-associated metallopeptidase involved in folate metabolism and epithelial transport-associated signaling pathways. Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

FOLH1 Antibody Dog Kidney IHC. Immunohistochemistry analysis of FFPE dog kidney tissue stained with FOLH1 Antibody / Prostate Cancer and PSMA Marker. Renal tubular epithelial cells display distinct apical membranous and cytoplasmic HRP-DAB brown staining consistent with expression of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA, a membrane-associated enzyme involved in folate metabolism and epithelial transport-related signaling pathways. Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

FOLH1 Antibody Cow Brain IHC. Immunohistochemistry analysis of FFPE cow brain tissue stained with FOLH1 Antibody / Prostate Cancer and PSMA Marker. Neural tissue demonstrates diffuse cytoplasmic and fibrillar HRP-DAB brown staining consistent with expression of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA, a glutamate carboxypeptidase involved in neuropeptide metabolism and glutamatergic signaling pathways within the nervous system. Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.

FOLH1 Antibody LNCaP WB. Western blot analysis of human LNCaP cell lysate using FOLH1 antibody. A strong band is detected at approximately 100 kDa, consistent with the predicted molecular weight of Folate hydrolase 1 / FOLH1, also known as Prostate-specific membrane antigen / PSMA. The observed signal is consistent with established FOLH1 expression in prostate-derived cell models and supports its role as a membrane-associated enzyme involved in folate metabolism and prostate cancer-associated signaling pathways.