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Home >> Antibodies >> Estrogen Receptor alpha Antibody

Estrogen Receptor alpha Antibody [clone 1D5] (V7746)

  Catalog No Formulation Size Price (USD)  
Image V7746-0.5ML Culture supernatant with 0.05% sodium azide 0.5 ml 519
Image
V7746-0.1ML Culture supernatant with 0.05% sodium azide 0.1 ml 229
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IHC staining of FFPE human endometrial carcinoma with Estrogen Receptor alpha antibody (clone 1D5). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human
Format Culture supernatant
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name 1D5
Purity Culture supernatant
UniProt P03372
Localization Nuclear
Applications Immunohistochemistry (FFPE) : 1:100-1:200
Limitations This Estrogen Receptor alpha antibody is available for research use only.
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Description

This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

Application Notes

Optimal dilution of the Estrogen Receptor alpha antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for this Estrogen Receptor alpha antibody.

Storage

Store the Estrogen Receptor alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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