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Home >> Antibodies >> EPCR Antibody / CD201

EPCR Antibody / CD201 (R32352)

  Catalog No Formulation Size Price (USD)  
Image R32352 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of human A549 cell lysate with EPCR antibody. Expected molecular weight ~24/36-46 kDa (unmodified/glycosylated). The ~52 kDa band may represent a further modification of the protein.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q9UNN8
Applications Western blot : 0.1-0.5ug/ml
ELISA : 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating
Limitations This EPCR antibody is available for research use only.
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Description

Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor), is a protein that in humans is encoded by the PROCR gene. It has also recently been designated CD201 (cluster of differentiation 201). The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. And it is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.

Application Notes

Optimal dilution of the EPCR antibody should be determined by the researcher.

Immunogen

Amino acids 18-210 of human EPCR/CD201 were used as the immunogen for the EPCR antibody.

Storage

After reconstitution, the EPCR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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