- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
EIF4E Antibody [clone 8C8-C10-C12] (F54054)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F54054-0.1ML | In PBS with 50% glycerol and 0.03% ProClin 300 | 0.1 ml | 439 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse lgG1 |
| Clone Name | 8C8-C10-C12 |
| Purity | Protein G affinity |
| UniProt | P06730 |
| Applications | Western Blot : 1:1000 |
| Limitations | This EIF4E antibody is available for research use only. |
|
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Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. [UniProt]
Additional EIF4E antibody formats and validation data are available on our main EIF4E Antibody page.
The stated application concentrations are suggested starting points. Titration of the EIF4E antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A human recombinant protein was used as the immunogen for this EIF4E antibody.
Store the EIF4E antibody at -20oC.
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