Dystrophin Antibody / Muscle Membrane Structural Protein Antibody [clone DMD/3241] (V7547)

Dystrophin Antibody Skeletal Muscle IHC. Immunohistochemistry analysis of FFPE skeletal muscle tissue using Dystrophin Antibody (clone DMD/3241) shows strong membranous staining outlining muscle fibers, consistent with dystrophin localization at the sarcolemma. The continuous circumferential staining pattern highlights intact muscle fiber membranes, while surrounding connective tissue displays minimal background signal. Hematoxylin counterstain provides nuclear contrast and tissue architecture. HIER: boil FFPE tissue sections in pH 6 10 mM citrate buffer for 10-20 min and allow to cool before testing.

Dystrophin Antibody HuProt Microarray Specificity. Protein microarray analysis using Dystrophin Antibody (clone DMD/3241) demonstrates highly specific binding to DMD / Dystrophin, with the target protein ranked as the top hit and showing a strong Z score with clear separation from all other proteins on the array. Signal intensity decreases sharply for non-target proteins, supporting selective recognition with minimal off-target interaction. Z score represents the strength of signal in standard deviations above the mean of all array signals, while S score reflects the separation between ranked targets and provides a measure of relative specificity.

SDS-PAGE analysis of purified, BSA-free Dystrophin antibody (clone DMD/3241) as confirmation of integrity and purity.

Dystrophin Antibody Skeletal Muscle Fiber IHC. Immunohistochemistry analysis of FFPE skeletal muscle tissue using Dystrophin Antibody (clone DMD/3241) shows reduced and discontinuous membranous staining along individual muscle fibers, consistent with altered dystrophin localization at the sarcolemma. The fragmented staining pattern contrasts with the continuous membrane outline typically observed in normal muscle, supporting detection of dystrophin in a context of compromised muscle fiber integrity. Hematoxylin counterstain provides nuclear contrast and tissue architecture. HIER: boil FFPE tissue sections in pH 6 10 mM citrate buffer for 10-20 min and allow to cool before testing.