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Home >> Antibodies >> DLL4 Antibody

DLL4 Antibody (F54165)

  Catalog No Formulation Size Price (USD)  
Image F54165-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F54165-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
Bulk quote request
Western blot testing of 1) mouse kidney, 2) mouse lung and 3) rat lung tissue lysate with DLL4 antibody at 1:2000. Predicted molecular weight: 75-85 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NR61
Applications Western Blot : 1:1000-1:2000
Limitations This DLL4 antibody is available for research use only.
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Description

Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.

Application Notes

The stated application concentrations are suggested starting points. Titration of the DLL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Recombinant human Delta-like protein 4 protein was used as the immunogen for the DLL4 antibody.

Storage

Aliquot the DLL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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