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Home >> Antibodies >> CREB1 Antibody

CREB1 Antibody [clone 1335CT115.203.189] (F52446)

  Catalog No Formulation Size Price (USD)  
Image F52446-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 429
Image
F52446-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 199
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Western blot analysis of lysate from 1) human A549, 2) mouse Neuro-2a, 3) mouse NIH3T3, and 4) rat C6 cell line using CREB1 antibody at 1:1000. Predicted molecular weight is 37 kDa but routinely observed at ~43 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, k
Clone Name 1335CT115.203.189
Purity Purified
UniProt P16220
Applications Western Blot : 1:1000
Limitations This CREB1 antibody is available for research use only.
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Description

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Application Notes

Titration of the CREB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This CREB1 antibody was produced from a mouse immunized with a recombinant protein from human CREB1.

Storage

Aliquot the CREB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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