Connective Tissue Growth Factor Antibody (F50760)

Connective Tissue Growth Factor Antibody WB. Western blot analysis of NCI-H460 cell lysate using Connective Tissue Growth Factor Antibody demonstrates a distinct immunoreactive band at approximately 38 kDa. The observed molecular weight is consistent with the predicted size of Connective Tissue Growth Factor (CTGF), also known as Cellular Communication Network Factor 2 (CCN2), a secreted matricellular protein involved in extracellular matrix regulation, tissue remodeling, wound healing, and cellular signaling. The strong, discrete band supports specific recognition of CTGF in human cells and demonstrates the utility of this antibody for studies of fibrosis, connective tissue biology, tumor microenvironment interactions, and extracellular matrix remodeling pathways.

Connective Tissue Growth Factor Antibody Hepatocellular Carcinoma IHC. Immunohistochemistry staining of FFPE human hepatocellular carcinoma tissue using Connective Tissue Growth Factor Antibody demonstrates moderate cytoplasmic HRP-DAB brown staining within malignant hepatocellular populations. The staining pattern is consistent with expression of Connective Tissue Growth Factor (CTGF), also known as Cellular Communication Network Factor 2 (CCN2), a matricellular protein involved in extracellular matrix regulation, tissue remodeling, cellular signaling, and tumor-stroma interactions. The observed immunoreactivity highlights CTGF expression within neoplastic cells and supports its established role in pathways associated with tumor progression, angiogenesis, wound healing, and extracellular matrix remodeling. This staining pattern demonstrates the utility of CTGF antibodies for studies of liver cancer biology, connective tissue signaling, and tumor microenvironment regulation.