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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Type IV collagen is the major structural component of the glomerular basement membrane (GBM), forming a hexagonal network together with lamins, proteoglycans, and nestin. Deletions of the N-terminal regions of COL4A5 and COL4A6 were found in Xq22.3 chromosome deletion syndrome and were located in an end-to-end manner. This results in a phenotype characteristic of diffuse leiomyomatosis and Alport syndrome (DL-ATS).
Optimal dilution of the COL4A5 antibody should be determined by the researcher.
A recombinant fragment (within amino acids 1400-1685) of human COL4A protein was used as the immunogen for the COL4A5 antibody.
Aliquot the COL4A5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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