- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Claudin18.2 Antibody [clone CLDN18.2/8014R] (V5008)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V5008-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
|
|
V5008-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
|
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V5008SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | CLDN18.2/8014R |
| Purity | Protein A/G affinity |
| UniProt | P56856 |
| Localization | Cell junction, Cell membrane |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This Claudin18.2 antibody is available for research use only. |
|
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Claudin18.2 Antibody specifically detects Claudin18.2 protein. The claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, occludin and junction adhesion molecule. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.
Explore our Claudin18.2 Antibody / Gastrointestinal Cancer Marker page for additional validation data and research applications involving gastric cancer, pancreatic cancer, epithelial tight junction biology, and therapeutic target-associated oncology pathways.
Optimal dilution of the Claudin18.2 antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 1-100) from the human protein was used as the immunogen for the Claudin18.2 antibody.
Store the Claudin18.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Claudin18.2 antibody, CLDN18.2 antibody, Claudin 18 isoform 2 antibody, Tight junction protein Claudin18.2 antibody, Claudin18 gastric cancer marker antibody
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