- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional co-receptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Titration of the CD8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 150-180 from the human protein was used as the immunogen for this CD8 antibody.
Aliquot the CD8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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