- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD3 epsilon Antibody / T Cell Activation Marker Antibody [clone EED-3] (RQ5185)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ5185 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 449 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Host | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | EED-3 |
| Purity | Affinity purified |
| UniProt | P07766 |
| Applications | Western Blot : 1:500-1:2000 |
| Limitations | This CD3 epsilon antibody is available for research use only. |
|
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CD3 epsilon (CD3E) is a critical signaling component of the T-cell receptor (TCR) complex that plays a central role in antigen recognition and activation of T lymphocytes. CD3 epsilon Antibody / T Cell Activation Marker Antibody enables detection of CD3 epsilon / CD3E and is widely used to study activation-dependent processes in T cells. CD3 epsilon antibody, also referred to as CD3E antibody, is commonly described as a T cell activation marker antibody because it directly participates in the signaling events that initiate T-cell activation.
This CD3 epsilon Antibody is uniquely positioned for investigating functional activation states of T lymphocytes. CD3 epsilon forms part of the CD3 signaling complex together with CD3 gamma, CD3 delta, and CD3 zeta chains, which associate with the TCR. Engagement of the TCR triggers phosphorylation-dependent signaling cascades that drive T-cell activation, proliferation, and differentiation into effector and memory subsets. Because CD3 epsilon is directly involved in these early activation events, its detection provides a biologically relevant readout of T-cell activation status.
As a T cell activation marker antibody, CD3 epsilon antibody reagents enable analysis of activation-associated changes in T-cell populations. Detection of CD3 epsilon supports studies of receptor engagement, signal initiation, and downstream functional responses such as cytokine production, clonal expansion, and effector differentiation. CD3 epsilon Antibody / T Cell Activation Marker Antibody is therefore particularly valuable in experimental systems designed to evaluate immune activation and response dynamics.
T-cell activation is tightly regulated and determines the outcome of adaptive immune responses. CD3 epsilon serves as a key mediator of signal transduction from the TCR to intracellular pathways that control T-cell function. Changes in CD3 epsilon signaling can influence activation thresholds, response magnitude, and immune regulation. This makes CD3 epsilon antibody a critical tool for studying how T cells transition between resting and activated states.
In experimental applications, CD3 epsilon antibody reagents are used to monitor activation dynamics in cultured T cells, primary lymphocytes, and tissue-derived immune populations. Detection of CD3 epsilon enables researchers to assess how experimental conditions influence T-cell activation and functional outcomes.
CD3 epsilon antibody can also be used in combination with additional activation or differentiation markers to provide a more comprehensive view of T-cell functional states. Integration with other readouts enables detailed characterization of immune activation and response profiles.
CD3 epsilon Antibody / T Cell Activation Marker Antibody provides a biologically informative and reliable tool for studying T-cell activation, supporting research focused on immune response, signaling pathways, and functional immunology.
A full range of CD3e antibody reagents for immunohistochemistry, western blot, and flow cytometry is available on our CD3e Antibody collection page.
Optimal dilution of the CD3 epsilon Antibody / T Cell Activation Marker Antibody should be determined by the researcher.
A synthetic peptide specific to human CD3 epsilon / CD3E was used as the immunogen for the CD3 epsilon Antibody / T Cell Activation Marker Antibody.
Store the CD3 epsilon antibody at -20oC.
CD3E antibody, CD3 epsilon activation marker antibody, CD3 T cell activation antibody, CD3 immune activation marker antibody, CD3 signaling activation antibody
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