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Home >> Antibodies >> CD28 Antibody

CD28 Antibody [clone CB28] (V2051CF488)

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  Catalog No Formulation Size Price (USD)  
Image V2051CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 519
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SDS-PAGE analysis of purified, BSA-free CD28 antibody (clone CB28) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free CD28 antibody (clone CB28) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format CF488 Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name CB28
Purity Protein G affinity chromatography
Applications Flow cytometry : 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood
Immunofluorescence : 1:50-1:100
Limitations This CD28 antibody is available for research use only.
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Description

Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Application Notes

Optimal dilution of the CD28 antibody should be determined by the researcher.

Immunogen

Recombinant human protein was used as the immunogen for this CD28 antibody.

Storage

Store the CD28 antibody at 2-8oC, protected from light.

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