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Home >> Antibodies >> CD21 Antibody

CD21 Antibody [clone CDLA21-1] (V3779)

  Catalog No Formulation Size Price (USD)  
Image V3779-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3779-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3779SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Bulk quote request
IHC testing of FFPE human tonsil tissue with CD21 antibody (clone CDLA21-1). HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name CDLA21-1
Purity Protein G affinity chromatography
UniProt P20023
Localization Cell surface
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This CD21 antibody is available for research use only.
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Description

CD21/CR2 is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. This mAb is highly specific to CR2 and shows no cross-reaction with CR1.

Application Notes

The stated application concentrations are suggested starting points. Titration of the CD21 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 44-196 were used as the immunogen for the CD21 antibody.

Storage

Store the CD21 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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