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Home >> Antibodies >> CD2 Antibody

CD2 Antibody [clone BH1] (V2032CF488)

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  Catalog No Formulation Size Price (USD)  
Image V2032CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 519
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Availability 1-3 business days
Species Reactivity Human
Format CF488 Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name BH1
Purity Protein G affinity chromatography
Applications Flow cytometry : 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood
Immunofluorescence : 1:50-1:100
Limitations This CD2 antibody is available for research use only.
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Description

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Application Notes

Optimal dilution of the CD2 antibody should be determined by the researcher.

Immunogen

Human CD2 protein was used as the immunogen of the CD2 antibody.

Storage

Store the CD2 antibody at 2-8oC, protected from light.

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