- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD163L1 Antibody / Macrophage Scavenger Receptor Antibody [clone CD163L1/7974] (V4247)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V4247-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 559 | |
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V4247-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 259 | |
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V4247SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG |
| Clone Name | CD163L1/7974 |
| Purity | Protein A/G affinity |
| UniProt | Q9NR16 |
| Localization | Cytoplasm |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT |
| Limitations | This CD163L1 Antibody / Macrophage Scavenger Receptor Antibody is available for research use only. |
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CD163 Like 1 (CD163L1) is a scavenger receptor family protein encoded by the CD163L1 gene and belongs to the scavenger receptor cysteine-rich superfamily. The CD163L1 Antibody is useful for investigating macrophage biology, innate immune responses, and receptor-mediated interactions within myeloid cell populations. CD163L1 is primarily localized to the plasma membrane and shares structural features with CD163, a well-characterized macrophage scavenger receptor, while exhibiting distinct expression patterns that suggest specialized biologic functions. Expression has been reported predominantly in cells of the monocyte-macrophage lineage, making CD163L1 a valuable target for studies of immune cell differentiation and tissue-resident macrophage populations.
CD163L1 antibody, also referred to as CD163 Like 1 antibody, M160 antibody, and macrophage scavenger receptor antibody in the literature, recognizes a transmembrane glycoprotein containing multiple scavenger receptor cysteine-rich domains. Clone CD163L/7974 antibody detects CD163L1 expression associated with monocyte and macrophage populations and is useful for investigations of innate immune regulation and myeloid cell function. These conserved cysteine-rich domains are characteristic of receptors involved in ligand recognition, cellular communication, and regulation of inflammatory responses. As a result, CD163L1 has attracted growing interest as a marker associated with specialized macrophage subsets and tissue immune homeostasis.
As a macrophage scavenger receptor family member, CD163L1 is believed to participate in interactions between immune cells and their extracellular environment. Scavenger receptors contribute to recognition and clearance of endogenous ligands, regulation of inflammatory signaling, removal of cellular debris, and maintenance of tissue homeostasis. Although the biologic functions of CD163L1 remain less extensively characterized than those of CD163, available evidence supports a role in innate immunity and macrophage-associated signaling pathways. The macrophage scavenger receptor differentiator is particularly relevant because CD163L1 expression has been linked to immune cell populations involved in tissue remodeling, wound repair, and host defense.
Macrophages are central regulators of inflammation, tissue regeneration, fibrosis, and immune surveillance. Proteins associated with distinct macrophage populations provide valuable tools for examining immune cell heterogeneity within normal and diseased tissues. Researchers continue to investigate whether CD163L1 expression identifies specialized macrophage subsets present within inflammatory lesions, regenerative environments, and tumor-associated microenvironments. Understanding how scavenger receptor family members contribute to immune regulation may provide additional insight into mechanisms controlling tissue homeostasis and disease progression.
Research involving CD163L1 continues to expand as investigators explore its roles in inflammatory disorders, immune regulation, and tissue repair. A CD163L1 antibody can support studies of macrophage biology, monocyte differentiation, scavenger receptor function, and innate immune signaling. General antibody-based approaches may be used to evaluate CD163L1 expression in a variety of research applications. NSJ Bioreagents offers clone CD163L/7974 antibody to support investigations of macrophage-associated pathways, immune cell specialization, and myeloid lineage biology.
Researchers interested in macrophage-associated receptors and related cluster of differentiation markers may also wish to explore our CD Antibodies landing page featuring antibodies against a broad range of immune cell surface proteins involved in leukocyte identification, differentiation, and signaling.
For additional targets involved in innate immunity, inflammatory regulation, and immune cell communication, visit our Immunology Antibodies landing page highlighting proteins that govern host defense and immune system function.
Optimal dilution of the CD163L1 Antibody / Macrophage Scavenger Receptor Antibody should be determined by the researcher.
A recombinant fragment of human CD163L1 protein was used as the immunogen for the CD163L1 antibody.
Aliquot the CD163L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
CD163 Like 1 antibody, M160 antibody, Scavenger receptor cysteine rich protein antibody, Monocyte scavenger receptor antibody, Macrophage receptor antibody
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