- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.
Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 235-263 from the human protein was used as the immunogen for this Caspase-6 antibody.
Aliquot the Caspase-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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