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Home >> Antibodies >> Caspase-6 Antibody

Caspase-6 Antibody (F42752)

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  Catalog No Formulation Size Price (USD)  
Image F42752-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
Image
F42752-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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Western blot analysis of Caspase-6 antibody and mouse liver tissue lysate. Predicted molecular weight: ~33 kDa (precursor).
IHC analysis of FFPE human hepatocarcinoma tissue stained with Caspase-6 antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Bovine, Rat
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P55212
Applications Western Blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This Caspase-6 antibody is available for research use only.
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Description

CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.

Application Notes

Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 235-263 from the human protein was used as the immunogen for this Caspase-6 antibody.

Storage

Aliquot the Caspase-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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