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Home >> Antibodies >> Caspase-6 Antibody

Caspase-6 Antibody (F42752)

  Catalog No Formulation Size Price (USD)  
Image F42752-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F42752-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of Caspase-6 antibody and mouse liver tissue lysate. Predicted molecular weight: ~33 kDa (precursor).
IHC analysis of FFPE human hepatocarcinoma tissue stained with Caspase-6 antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Rat, Bovine
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P55212
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This Caspase-6 antibody is available for research use only.
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Description

CASP6 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein could be processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade.

Application Notes

Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 235-263 from the human protein was used as the immunogen for this Caspase-6 antibody.

Storage

Aliquot the Caspase-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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