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Home >> Antibodies >> BMP6 Antibody

BMP6 Antibody (R32014)

  Catalog No Formulation Size Price (USD)  
Image R32014 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human HeLa cell lysate with BMP6 antibody. Expected molecular weight: ~57 kDa (precursor), ~46 kDa (cleaved precursor), 18-23 kDa (mature).
Flow cytometry testing of human HeLa cells with BMP6 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=BMP6 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P22004
Applications Western blot : 0.1-0.5ug/ml
Flow Cytometry : 1-3ug/10^6 cells
ELISA : 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating
Limitations This BMP6 antibody is available for research use only.
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Description

Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Application Notes

Optimal dilution of the BMP6 antibody should be determined by the researcher.

Immunogen

Amino acids QSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYV of human BMP6 were used as the immunogen for the BMP6 antibody.

Storage

After reconstitution, the BMP6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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