- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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This BMI-1 Antibody is a protein microarray validated monoclonal antibody specific to B cell-specific moloney murine leukemia virus integration site 1 (Bmi-1), a transcriptional receptor of the polycomb gene family involved in several cellular processes including cell-cycle regulation, apoptosis, and maintenance of adult and neoplastic stem cells by providing self-renewal capacity. Further, Bmi-1 expression has been associated with malignant transformation, tumor progression, metastatic disease, and poor prognosis in human malignancies.
Additional studies involving polycomb-mediated transcriptional repression, stem cell renewal, and epigenetic regulation pathways may benefit from our BMI1 antibody page featuring clone BMI1/2823 with HuProt protein microarray specificity validation.
Optimal dilution of the BMI-1 Antibody / Protein Microarray Validated Antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
A portion of amino acids 142-326 from the human protein was used as the immunogen for the BMI-1 antibody.
Store the BMI-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
BMI1 polycomb antibody, B lymphoma Mo-MLV insertion region 1 antibody, PCGF4 antibody, BMI1 stem cell marker antibody, BMI1 cancer stem cell antibody, polycomb group protein BMI1 antibody
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