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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).
The stated application concentrations are suggested starting points. Titration of the ATF7IP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 318-347 from the human protein was used as the immunogen for the ATF7IP2 antibody .
Aliquot the ATF7IP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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