- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ASCL1 Antibody / MASH1 (F47525)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F47525-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 379 | |
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F47525-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 165 |
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| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P50553 |
| Applications | Western blot : 1:1000 |
| Limitations | This ASCL1 antibody is available for research use only. |
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This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Titration of the ASCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.
Aliquot the ASCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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