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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Apolipoprotein E is also known as APOE, AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.
Optimal dilution of the Apolipoprotein E antibody should be determined by the researcher.
E. coli-derived recombinant human protein (amino acids E95-Q222) was used as the immunogen for the Apolipoprotein E antibody.
After reconstitution, the Apolipoprotein E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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