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Home >> Antibodies >> ApoE Antibody

ApoE Antibody (R31740)

  Catalog No Formulation Size Price (USD)  
Image R31740 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of ApoE antibody and human placenta lysate. Predicted molecular weight: 34-37 kDa.
IHC-P: ApoE antibody testing of human placenta tissue
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Gene ID 348
Localization Cytoplasmic, membranous
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
ELISA (Capture :
recombinant human protein) : 1-5ug/ml
Limitations This ApoE antibody is available for research use only.
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Description

Apolipoprotein E, also known as AD2 or LPG, is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in ApoE result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple ApoE transcript variants.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human partial recombinant protein (AA 19-317) was used as the immunogen for this ApoE antibody.

Storage

After reconstitution, the ApoE antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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