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Home >> Antibodies >> Anti-PCSK9 Antibody

Anti-PCSK9 Antibody (F50318)

  Catalog No Formulation Size Price (USD)  
Image F50318-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329
Image
F50318-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of lysate from HeLa cell line using anti-PCSK9 antibody at 1:1000. Predicted size: Pro/mature ~74/64 kDa
Western blot analysis of lysate from HepG2 cell line using anti-PCSK9 antibody at 1:1000. Predicted size: Pro/mature ~74/64 kDa
IHC analysis of FFPE human colon carcinoma section using anti-PCSK9 antibody; Ab was diluted at 1:100.
Anti-PCSK9 antibody IHC analysis in formalin fixed and paraffin embedded human colon carcinoma.
Anti-PCSK9 antibody flow cytometric analysis of HeLa cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q8NBP7
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:100
Flow Cytometry : 1:10-1:50
Limitations This anti-PCSK9 antibody is available for research use only.
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Description

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Application Notes

The stated application concentrations are suggested starting points. Titration of the anti-PCSK9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 479-508 from the human protein was used as the immunogen for this anti-PCSK9 antibody.

Storage

Store at 4oC for up to one month. For long term, aliquot the anti-PCSK9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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