AMBP Antibody / Plasma Glycoprotein Marker Antibody [clone AMBP/4533] (V5300)

AMBP Antibody Protein Microarray Validation. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using AMBP Antibody demonstrates highly selective recognition of Alpha-1-microglobulin-bikunin precursor / AMBP with exceptionally strong separation from non-target proteins across the tested human proteome. This plasma glycoprotein marker antibody produced the strongest binding signal for AMBP, with substantially lower Z-scores observed for unrelated proteins including Ubiquitin and STON2, supporting preferential target recognition. These results demonstrate the foremost specificity of the AMBP/4533 mAb and support highly specific detection of extracellular glycoprotein-associated signaling pathways. The Z-score represents the strength of antibody binding signal relative to the overall array mean, while the S-score reflects target specificity relative to the next highest ranked protein signal. The markedly elevated S-score separation observed for AMBP supports minimal off-target binding across the tested human proteome.

SDS-PAGE analysis of purified, BSA-free AMBP antibody (clone AMBP/4533) as confirmation of integrity and purity.

AMBP Antibody Ovarian Cancer IHC. Immunohistochemistry analysis of formalin-fixed, paraffin-embedded human ovarian carcinoma tissue stained with AMBP Antibody demonstrates prominent cytoplasmic HRP-DAB brown staining within tumor epithelial cell populations, consistent with Alpha-1-microglobulin-bikunin precursor / AMBP-associated extracellular glycoprotein expression. Surrounding stromal components demonstrate comparatively weaker staining, supporting enrichment of AMBP-associated secretory pathway signaling within neoplastic epithelial structures. This plasma glycoprotein marker antibody highlights extracellular regulatory signaling and secretory protein-associated biology in ovarian cancer tissue. Inset: PBS used in place of primary antibody demonstrates minimal background staining in the negative control section. Heat-induced epitope retrieval was performed by boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min followed by cooling prior to antibody incubation.